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When does brain development begin?

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Brain development begins with the formation and closure of the neural tube, the earliest nervous tissue that looks like a fat earthworm stretched out along the entire back of the embryo.

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The neural tube forms from the neural plate, which begins forming just sixteen days after conception. This plate lengthens and starts folding up, forming a groove at around eighteen days, which then begins fusing shut into a tube around twenty-two days post-conception. By 27 days, the tube is fully closed and has already begun its transformation into the brain and spinal cord of the embryo.

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